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The principal cytochrome P450 isoenzyme associated appears to get CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Somewhere around eighty five% of the oral dose appears while in the urine inside 24 hours of administration, most as being the glucuronide conjugate, with little amounts of other conjugates and unchanged drug (see OVERDOSAGE) f